Gingival crevicular fluid level of medullasin, an elastase-like serine proteinase.

Gingival Crevicular Fluid Biomarkers

Material and Method: Thirty patients were allocated into 3 groups: 10 were treated with scaling and root planing (SRP) only; 10 were treated with SRP and received adjunctive local metronidazole; 10 were treated with SRP and received adjunctive systemic metronidazole. Periodontal clinical parameters including plaque index, sulcus bleeding index, probing depth and relative attachment level were r...

an evaluation on elastase enzyme activity in gingival crevicular fluid in periodontitis

statement of problem: changes in protein levels, host calls enzymes and inflammatory mediators in gingival crevicular fluid (gcf) are considered as diagnostic indicators of periodontitis.purpose: he aim of the present study was to measure the elastase enzyme activity in gingival crevicular fluid among patients with periodontitis.material and methods: in this study, 52 periodontitis patients (ex...

Hydroxyproline titers in gingival crevicular fluid.

The Effect of Tobacco Smoking on Gingival Crevicular Fluid Volume

OBJECTIVES The negative effects of smoking on periodontal health are well known. But the mechanism is not clear yet. The aim of the present study is to investigate the effects of smoking on gingival crevicular fluid (GCF) volume. METHODS The study included 26 age and gender matched periodontally healthy males. Half of the participants were smokers and the others were non-smokers. After period...

Periodontal pathogens affect the level of protease inhibitors in gingival crevicular fluid.

In periodontitis, an effective host-response is primarily related to neutrophils loaded with serine proteases, including elastase (NE) and protease 3 (PR3), the extracellular activity of which is tightly controlled by endogenous inhibitors. In vitro these inhibitors are degraded by gingipains, cysteine proteases produced by Porphyromonas gingivalis. The purpose of this study was to determine th...